Northstar Select®

Therapy Selection

Northstar Select is a highly sensitive ctDNA liquid biopsy that uses QCTTM technology to guide therapy selection by detecting actionable alterations, even in low tumor fraction samples. 

50% Reduction in false negative results
109% More actionable CNVs detected

A purpose-built liquid biopsy
Northstar Select® uncovers treatment opportunities others miss—focused on the genes that matter most for therapy selection.

  • Appropriate for all late-stage solid tumor cancers
  • 2x - 5x lower LoD than comparator assays2
  • Comprehensive 84 gene panel covering:
    • 82 genes for single nucleotide variants (SNVs) /indels
    • 19 genes for copy number amplifications
    • 5 genes for copy number loss
    • 9 genes for fusions
    • MSI status (microsatellite instability biomarker)
  • Results typically within 10 days

The most sensitive liquid biopsy proven to uncover 50%+ more clinically actionable alterations.

Proven to Detect More
Northstar Select was clinically validated in a head-to-head study1 compared with other commercially available liquid biopsy assays. Results demonstrated:

  • 51% more SNV/indels detected by Northstar Select
  • 109% more copy number alterations 
  • ~2x fewer false negatives
  • Significantly higher detection rates at VAFs below 0.2% where most liquid biopsies miss clinically actionable alterations